The product was tested by HSA to contain sibutramine and phenolphthalein, which are potent, undeclared western medicinal ingredients. Sibutramine, a prescription-only weight loss drug, has been banned in Singapore since due to serious safety concerns.
The seller is currently assisting HSA with the investigation. Please refer to the attached pdf for the picture of the product. Sibutramine was a prescription medicine previously used as an appetite suppressant in the management of obesity and has been banned for sale in Singapore since October because of safety concerns associated with cardiovascular risks.
It may cause serious adverse effects, including high blood pressure, increased heart rate, anxiety, heart attacks and irregular heartbeats. Changes in mood such as anxiety, depression and mood swings have also been reported.
Phenolphthalein may cause rashes, abdominal cramps, breathing difficulties, kidney disorders and has been found in animal studies to be associated with cancer. It cannot be ascertained where and how these products were made. II Not consume health products that promise quick and miraculous weight loss. Garcinia cambogia contains an organic acid called HCA, which may promote weight loss by suppressing appetite and enhancing fat oxidation.
However, its effectiveness has been called into question in recent research. Although some earlier studies demonstrated that garcinia cambogia and HCA had powerful suppressive effects on calorie intake and enhanced weight loss and fat burning, more current reviews have not shown consistent results.
Additionally, a study in 60 adults observed that treatment with an HCA supplement that provided 2, mg of the compound per day for 8 weeks led to a 5.
Furthermore, other older studies with small sample sizes indicate that HCA may suppress fat accumulation 9 , Yet, most of the studies that have noted positive results have used small sample sizes and were performed over short periods of less than 3 months Plus, other studies show that HCA and garcinia cambogia supplements have no beneficial effects on calorie intake, fat burning, or weight loss, adding more doubt that these supplements promote fat loss 12 , 13 , 14 , 15 , Given the contradictory findings and overall lack of large, long-term, well-designed studies, research reviews have consistently reported that not enough evidence is available to suggest that garcinia cambogia is an effective tool for weight loss 2 , For example, an update article that included a review of 22 studies revealed that both HCA and garcinia cambogia had limited or no effects on weight loss, feelings of fullness, or calorie intake in human studies 2.
Another review of 9 studies found treatment with garcinia cambogia resulted in small yet significant short-term decreases in weight loss compared with a placebo. Yet, this significance was not observed when only well-designed randomized controlled trials were evaluated Thus, based on the most recent findings, the overall effect of garcinia cambogia and HCA on weight loss is small at best, and the clinical relevance of the positive findings related to garcinia cambogia and HCA are questionable Some research suggests that garcinia cambogia and HCA may promote short-term weight loss, but reviews of literature and well-designed studies have found limited or no benefit.
Therefore, these supplements cannot be recommended with certainty. Although some research demonstrates that garcinia cambogia and HCA supplements are safe, there have been reports of toxicity related to the ingestion of high doses of the supplement.
A review of 17 studies including people concluded that HCA did not cause adverse effects at dosages up to 2, mg per day However, garcinia cambogia supplements have been linked to liver failure and other adverse effects in other, more recent studies. One such case resulted after a year-old man consumed 2, mg of a supplement containing garcinia cambogia extract daily for 5 months.
The man experienced severe drug-induced liver failure and required a transplant 1. Another case of liver toxicity involved a year-old woman with no history of liver disease. The woman developed acute hepatitis after consuming 2, mg of pure garcinia cambogia extract daily for 1 month to promote weight loss.
The condition resolved when the women stopped taking the supplement. Yet, after 6 months, she resumed taking the same dose to promote weight loss, which again resulted in liver injury Additionally, there have been many other cases of liver toxicity related to supplementing with multi-ingredient supplements that contained HCA HCA was also the main ingredient in older formulations of Hydroxycut, a popular dietary supplement that caused 23 known cases of liver toxicity.
Although the supplement also contained ephedra , which the FDA banned in , 10 of the 23 cases that resulted in liver toxicity — one of which resulted in death — were reported after the removal of ephedra from the product 1. This led the producers of Hydroxycut to remove HCA from the currently available formulation. HCA and garcinia cambogia products have also been linked to side effects, including digestive upset, headaches, and upper respiratory tract symptoms.
These supplements may also interact with common medications, including drugs used to treat cancer, viruses, and pain As you can see, garcinia cambogia and HCA supplements have been associated with a host of side effects and may interact with commonly prescribed medications.
For these reasons, using this controversial supplement to promote weight loss may not be worth the potential risks. Garcinia cambogia and HCA supplements have been linked to liver toxicity and other potentially dangerous side effects. The products may also interact with commonly prescribed medications.
Although some research demonstrates that garcinia cambogia and its main organic acid HCA may support weight loss via several mechanisms, many studies have found that these products are ineffective and may even be downright dangerous when taken in high doses.
This means that some garcinia cambogia products may contain hidden ingredients, such as active compounds found in prescription drugs, as well as ingredients that have been removed from the market due to safety concerns 23 , For example, decreasing your intake of sweetened beverages, highly processed foods, and refined carbs, as well as increasing your intake of fiber , healthy fat, and proteins, are healthy ways to encourage weight loss.
Also, increasing your daily physical activity, getting enough sleep, and ensuring proper hydration by drinking enough water are smart ways to promote fat loss and overall health.
Remember, although the market is saturated with products promising rapid weight loss, reaching a healthy weight is not supposed to be quick, especially when you have a lot of excess body fat to lose.
Research has called into question the safety and efficacy of garcinia cambogia and HCA supplements. Garcinia cambogia and its main organic acid HCA are popular dietary supplements used to boost weight loss.
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